
Upendranath Brahmachari
Born 19 December 1873 · West Bengal
Died 6 February 1946
Synthesized urea-stibamine in 1922 to effectively treat kala-azar.
🔔 Add birthday reminderRai Bahadur Sir Upendranath Brahmachari ; 19 December 1873 – 6 February 1946) was a prominent Indian physician and scientist. In 1922, he synthesised urea-stibamine (carbostibamide) and demonstrated its effectiveness in treating kala-azar.
✨ A detail that surprised us
Upendranath Brahmachari regarded his modest laboratory as a “place of worship,” underscoring the sacredness with which he approached his research.
1. In 1922, at Calcutta, Upendranath Brahmachari synthesized urea-stibamine, a compound that transformed treatment for kala-azar, a deadly parasitic disease devastating Bengal and Assam.
2. 🎓 Before this breakthrough, Brahmachari earned a BA with honors in Mathematics and Chemistry from Hooghly Mohsin College in 1893 and an MD from the University of Calcutta in 1902, excelling in both Medicine and Surgery in 1900.
3. 🦠 In 1922, he identified a new form of leishmaniasis—post-kala-azar dermal leishmaniasis—marked by facial eruptions without fever, expanding scientific understanding of the disease’s manifestations.
4. 🏅 Awarded the Kaisar-i-Hind Gold Medal and Rai Bahadur title in 1924, Brahmachari was knighted by the British Government in 1934, yet was nominated but never received the Nobel Prize despite multiple nominations in 1929 and 1942.
5. He served as president of the Indian Science Congress and Indian Chemical Society in 1936 and held fellowships with the Royal Society of Medicine, London, and the Indian National Science Academy, reflecting his standing in scientific circles.
6. After retiring from Calcutta Medical College in 1927, he continued teaching tropical diseases at Carmichael Medical College, contributing to medical education in Bengal until his death in 1946.
7. A six-story building at Nil Ratan Sircar Medical College and Hospital is named after him, housing emergency and specialty departments, linking his legacy directly to modern medical care in Kolkata.
8. ❓ How did Brahmachari’s ethnicity and colonial context influence the international recognition of his life-saving discovery, and why does his legacy remain less celebrated globally despite his Nobel nominations?
Awards & Honours
- 🏅title of Rai Bahadur and the Kaisar-i-Hind Gold Medal
🔍 One thing most people don't know
Brahmachari was nominated for the Nobel Prize twice in 1929 and five times in 1942, yet never received it, with some sources suggesting his ethnicity influenced the Nobel committee's decisions.
🖼️ Through the Years
📅 The Journey
🗝️ Discoveries
🎥 Speeches & Recordings
History of Upendranath Brahmachari | Tamil
YouTube📖 Curated Sources
🌱 What changed because of them
Brahmachari’s synthesis of urea-stibamine revolutionized kala-azar treatment, saving countless lives in India and beyond. His work influenced tropical medicine education at institutions like Carmichael Medical College and remains commemorated through infrastructure like the building named after him at Nil Ratan Sircar Medical College. Despite British honors, his contributions highlight challenges Indian scientists faced in gaining international recognition during colonial times.
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